課程資訊
課程名稱
 組織工程原理
Principles of Tissue Engineering 
開課學期
 99-2 
授課對象
 工學院  化學工程學研究所  
授課教師
 游佳欣 
課號
 ChemE7033 
課程識別碼
 524EM6120 
班次
  
學分
 3 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期一6,7,8(13:20~16:20) 
上課地點
 工綜205 
備註
 本課程以英語授課。建議修過生物相關選修。
總人數上限：25人 
Ceiba 課程網頁
 http://ceiba.ntu.edu.tw/992Jia 
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課程概述

Tissue engineering is the application of life sciences and engineerings to develop biological substitutes for the restoration, maintenance, modification, improvement or replacement of tissue and organ function. We will introduce the principles of tissue engineering in this course as well as the current progress of stem cell and regenerative medicine. 

課程目標
 1. Understand the fundamentals of Tissue and Cell engineering.
2. Understand biomaterials,scaffolds and extracellular matrix(ECM)
3. Learn the characterization of cells and tissue.
4. Design the bioreactor and artificial organ. 
課程要求
 Students with biological related coursed are suggested. For senior undergraduate students interested in multidisciplinary researches, class codes can be requested from the instructor at the beginning of the semester. 
預期每週課後學習時數
  
Office Hours
  
指定閱讀
 to be added 
參考書目
 1.Principles of Tissue Engineering. Lanza,Langer and Vacanti
2.Biomaterials Science. An Indroduction to Materials in Medicine.Ratner and Hoffman
3.Tissue Engineering. Palsson and Bhatia 
評量方式
(僅供參考)
    
課程進度
週次
日期
單元主題
第1週
 2/21  [Introduction] Course overview and introduction 
第2週
 2/28  [Cell and Tissue Characterization I]
Cell-cell communication and tissue maintenance
 
第3週
 3/07  [Cell and Tissue Characterization II]
Quantitative analysis of cellular functions 
第4週
 3/14  [Cell and Tissue Characterization III]
Cell sources and stem cells 
第5週
 3/21  [Cell-ECM Interaction I]
Extracellular matrices: chemical and mechanical properties
 
第6週
 3/28  [Cell-ECM Interaction II]
Cell adhesion, ECM micropatterning and cell functions
 
第7週
 4/04  [Cell-ECM Interaction III]
Cell adhesion and migration 
第8週
 4/11  [In vitro Cell and Tissue Engineering I]
Bioreactors 
第9週
 4/18  [In vitro Cell and Tissue Engineering II]
Artificial skin and artificial liver 
第10週
 4/25  [In vitro Cell and Tissue Engineering IV]
Cardiac and vascular engineering 
第11週
 5/02  [In vitro Cell and Tissue Engineering V]
Angiogenesis. Mechanical regulation of cell functions 
第12週
 5/09  [In vivo Cell and Tissue Engineering I]
Growth factor delivery 
第13週
 5/16  [In vivo Cell and Tissue Engineering II]
Gene therapy 
第14週
 5/23  [In vivo Cell and Tissue Engineering III]
Bone repair
 
第15週
 5/30  [In vivo Cell and Tissue Engineering IV]
Nerve regeneration 
第16週
 6/06  [Final Project] Group Presentation 1 
第17週
 6/13  [Final Project]Group Presentation 2